Synthesis and structure of 4-(het)aryl-6-methyl-2-cyanoimino-N,N-diethyl-1,2,3,4-tetrahydropyrimidine-5-carboxamides
A series of previously unknown 4-(het)aryl-6-methyl-2-cyanoimino-N,N-diethyl-1,2,3,4-tetrahydropyrimidine-5-carboxamides was synthesized by the reaction of N,N-diethyl-3-oxobutanamide with (het)arylaldehydes and N-cyanoguanidine. The structure of the obtained compounds was established by IR, 1H NMR spectroscopy and single crystal X-ray diffraction analysis.
Authors
- N. A. Buzmakova (ORCID: https://orcid.org/0000-0003-3171-0438)
- М. В. Дмитриев (ORCID: https://orcid.org/0000-0002-8817-0543)
- Ф. В. Собин (ORCID: https://orcid.org/0000-0002-8416-6934)
- N. V. Slepova (ORCID: https://orcid.org/0000-0003-3924-3715)
- Т. М. Замараева (ORCID: https://orcid.org/0000-0002-9932-9628)
Institutions
- Ministry of Health of the Russian Federation (RU)
- Perm State Pharmaceutical Academy (RU)
Publication Details
- Journal
- Журнал Общей Химии
- Published
- 2024-10-14
- DOI
- https://doi.org/10.31857/s0044460x24050028
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.00