Cytotoxic compounds from <i>Viscum coloratum</i> (Kom.) Nakai

Two new compounds (<b>1</b>-<b>2</b>) and a new artificial product (<b>3</b>) together with fifteen known compounds (<b>4</b>-<b>18</b>) were isolated from <i>Viscum coloratum</i> (Kom.) Nakai. Their structures were established by analysis of their spectroscopic data including MS, 1D and 2D NMR spectra, and comparison with existing literature. All the compounds were assessed for their cytotoxic activity against 4T1 and LN229 cells (with cisplatin as the positive control), and the anti-LN229 cytotoxicity of compounds <b>3</b>, <b>4</b> and <b>5</b> were greater than that of 4T1 cells.

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Publication Details

Journal
Zeitschrift für Naturforschung C
Published
2024-11-13
DOI
https://doi.org/10.1515/znc-2023-0170
Primary Topic
Toxin Mechanisms and Immunotoxins
Type
article
Field-Weighted Citation Impact
0.00

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article

Cytotoxic compounds from Viscum coloratum (Kom.) Nakai

Zhichao Hao, Bo Wen, Bing-You Yang, Lili Zhang et al.
Zeitschrift für Naturforschung C
Toxin Mechanisms and Immunotoxins
article

Cytotoxic compounds from Viscum coloratum (Kom.) Nakai

Zhichao Hao, Bo Wen, Bing-You Yang, Lili Zhang, Yan Liu, Wei Guan, Xin Meng, Qingshan Chen, Hai‐Xue Kuang, Juan Pan
article en

Abstract

Two new compounds (<b>1</b>-<b>2</b>) and a new artificial product (<b>3</b>) together with fifteen known compounds (<b>4</b>-<b>18</b>) were isolated from <i>Viscum coloratum</i> (Kom.) Nakai. Their structures were established by analysis of their spectroscopic data including MS, 1D and 2D NMR spectra, and comparison with existing literature. All the compounds were assessed for their cytotoxic activity against 4T1 and LN229 cells (with cisplatin as the positive control), and the anti-LN229 cytotoxicity of compounds <b>3</b>, <b>4</b> and <b>5</b> were greater than that of 4T1 cells.

Zeitschrift für Naturforschung CVol. 80(7-8)
Northeast Agricultural University (CN), Heilongjiang University of Chinese Medicine (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 74%
Toxin Mechanisms and Immunotoxins
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