Development of a Nomogram Based on Transcriptional Signatures, IFN-γ Response and Neutrophils for Diagnosis of Tuberculosis
A nomogram composed of IGRA, percentage of neutrophils, and expression of CD64, GZMA, and PRDM1 was established. The nomogram demonstrated a sensitivity and specificity of 81% and 87%, respectively, for differentiating TB from controls.
Authors
- Fei Zhai
- Jin Jiang (ORCID: https://orcid.org/0000-0001-7078-5999)
- Jiyan Su (ORCID: https://orcid.org/0000-0002-2373-7924)
- Lingxia Zhang (ORCID: https://orcid.org/0000-0002-5012-7283)
- Wenna Sun
- Bo Yang (ORCID: https://orcid.org/0000-0002-3183-5567)
- Zhihong Cao (ORCID: https://orcid.org/0000-0002-6066-1834)
- Yanhua Liu (ORCID: https://orcid.org/0000-0003-1104-284X)
- Xiaoxing Cheng (ORCID: https://orcid.org/0000-0002-7036-4286)
Institutions
- Chinese PLA General Hospital (CN)
- Beijing Chest Hospital (CN)
- The 309th Hospital of Chinese People's Liberation Army (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/jir.s480173
- Citations
- 3
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.17