Protective Effect of Modified Suanmei-Tang on Metabolic-Associated Fatty Liver Disease: An Integrated Strategy of Network Pharmacology, Metabolomics, and Transcriptomics
MST could effectively improve lipid metabolism disorders and liver lipid deposition in MAFLD mice, and its mechanism might be related to regulating the PI3K/AKT/mTOR pathway to improve autophagy.
Authors
- Yong Zhang (ORCID: https://orcid.org/0000-0003-3704-4835)
- Yaqi Luo
- Yang Yang (ORCID: https://orcid.org/0000-0002-9911-7123)
- Chao Wang (ORCID: https://orcid.org/0000-0001-8452-1214)
- Zhongyi Zhang (ORCID: https://orcid.org/0000-0002-6375-2969)
- Mei Zhao
- Yantao He (ORCID: https://orcid.org/0000-0002-2692-0345)
- Yuanyuan Yue (ORCID: https://orcid.org/0000-0002-3797-9238)
- Tao Shen (ORCID: https://orcid.org/0000-0001-9487-884X)
- Chao Hu
- Sijie Dang
- Chunqiu Zhou
Institutions
- Xinjiang Medical University (CN)
- Third People's Hospital of Chengdu (CN)
- Sixth Affiliated Hospital of Xinjiang Medical University (CN)
- Sichuan Academy of Traditional Chinese Medicine (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/dddt.s478072
- Citations
- 5
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.93