Effect of vitamin C injections on exercise muscular performance and biochemical parameters in <i>Trichinella spiralis</i>-infected mice

Vitamin C enhances the weakness of the muscular performance resulting from the infection. Vitamin C was able to repair some of the histological lesions that resulted from the infection. Trichinellosis caused severe changes in the biochemical markers in positive control animals. Muscle damage biomarkers and, besides, oxidative and antioxidant conditions were greatly ameliorated in infected vitamin C animals. Summing up, vitamin C can be used as a complementary drug due to its efficiency in improving pathogenesis following a trichinellosis infection. The supplement also must be tested in the intestinal stage of infection after showing promising results in the muscular stage.

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Publication Details

Journal
PeerJ
Published
2024-11-13
DOI
https://doi.org/10.7717/peerj.18381
Primary Topic
Parasitic Diseases Research and Treatment
Type
article
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article

Effect of vitamin C injections on exercise muscular performance and biochemical parameters in Trichinella spiralis-infected mice

R. Fouad, Bander Albogami, Ali H. Abu Almaaty, Eman Elsayed Fayad et al.
PeerJ
Parasitic Diseases Research and Treatment
article

Effect of vitamin C injections on exercise muscular performance and biochemical parameters in Trichinella spiralis-infected mice

R. Fouad, Bander Albogami, Ali H. Abu Almaaty, Eman Elsayed Fayad, Samah S. Abuzahrah, Abdulsalam A. M. Alkhaldi, Fawziah A. Al‐Salmi, Hadeer Abd El-Hak Rashed, Abd-Allah Ahmed ElSaey, Najlaa Y. Abuzinadah, Manar Elsayed Fikry
article en

Abstract

Vitamin C enhances the weakness of the muscular performance resulting from the infection. Vitamin C was able to repair some of the histological lesions that resulted from the infection. Trichinellosis caused severe changes in the biochemical markers in positive control animals. Muscle damage biomarkers and, besides, oxidative and antioxidant conditions were greatly ameliorated in infected vitamin C animals. Summing up, vitamin C can be used as a complementary drug due to its efficiency in improving pathogenesis following a trichinellosis infection. The supplement also must be tested in the intestinal stage of infection after showing promising results in the muscular stage.

PeerJVol. 12
Taif University (SA), Jouf University (SA), University of Jeddah (SA), Port Said University (EG)
Good health and well-being
Openalex Percentile: Top 74%
Parasitic Diseases Research and Treatment
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Effect of vitamin C injections on exercise muscular performance and biochemical parameters in <i>Trichinella spiralis</i>-infected mice — R. Fouad, Bander Albogami, et al. · PeerJ (2024) | TGRS Research Map | TGRS