COMPARISON OF FENTANYLAND BUTORPHANOL IN ATTENUATING THE HAEMODYNAMIC RESPONSES TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION

Introduction: Laryngoscopy and intubation of the tracheal tube are noxious stimuli and changes in haemodynamics are attributed to the stimulation of epipharyngeal and parapharyngeal region. These changes are manifested as rise in heart rate and blood pressure which are variable, transient and unpredictable. Method: A double-blind randomised trial comparing the haemodynamic effects of two opioid drugs, Fentanyl and Butorphanol. 60 patients divided into two group. Group B- Inj. Butorphanol 40 µg/kg IV. Group F - Inj. Fentanyl 2 µg/kg IV. Is administered 5 minutes before Laryngoscopy Intubation. Results: Even in well-anaesthetised individuals, reex tachycardia and hypertension on laryngoscopy and intubation occurs quite frequently.The study was done on the focus to search for a better haemodynamic response so that patients compliance will be better with less side effects. Conclusion: With this study we conclude that the administration of intravenous butorphanol prior to induction of anaesthesia helps on better attenuation of the haemodynamic response to laryngoscopy and endotracheal intubation than intravenous fentanyl.