CLINICAL STUDY OF PATIENTS WITH LIVER ABSCESS AT A TERTIARY CARE CENTER

This study was conducted to evaluate etiology, clinical features, risk factors, imaging findings, bacteriologic profile, treatment, and outcome in patients presenting with liver abscesses. A prospective study of 53 patients (49 males and 4 females) with liver abscesses, that were hospitalized between April 2021 and March 2022 at our institute. The most significant clinical features of liver abscesses were upper abdominal pain with highgrade fever, icterus and hepatomegaly. Of the 53 cases, 16 had amebic abscess with Anchovy sauce-colored pus and 37 had pyogenic liver abscesses. All patients who had received intravenous antibiotic therapy (cephalosporin or fluoroquinolones in combination with metronidazole), showed a good response to this regime. Among the pyogenic liver abscess of 37 cases, 7 cases were treated conservatively with antimicrobials alone; 20 cases were treated with percutaneous needle aspiration; 8 cases were treated with percutaneous drainage; and 2 cases underwent laparotomy and drainage for ruptured liver abscess.