Epileptiform activity in brain organoids derived from patient with Glucose Transporter 1 Deficiency Syndrome
These findings validate the use of brain organoids as a model for studying GLUT1-DS and highlight their potential for testing novel therapeutic strategies aimed at improving glucose metabolism and managing epilepsy in patients.
Authors
- Sylvain Lengacher
- Luc Stoppini (ORCID: https://orcid.org/0000-0002-2648-7051)
- Frédéric Friscourt (ORCID: https://orcid.org/0000-0002-0749-0861)
- Pierre Julius Magistretti (ORCID: https://orcid.org/0000-0002-6678-320X)
- Charles Quairiaux (ORCID: https://orcid.org/0000-0003-3770-8232)
- Yves A. Muller (ORCID: https://orcid.org/0000-0003-0519-8928)
- Charles Finsterwald
- L. Lengacher
Institutions
- University of Geneva (CH)
- HES-SO University of Applied Sciences and Arts Western Switzerland (CH)
- HES-SO Genève (CH)
- Debiopharm (Switzerland) (CH)
- University Hospital of Geneva (CH)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fnins.2024.1498801
- Citations
- 5
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.63