A new ex vivo human skin model for the topographic and biological analysis of cosmetic formulas

The Perfex setup allows for similar preservation of skin explant histology and key protein expression as the conventional system, yet it maintains a skin surface close to that of in vivo skin. Therefore, it is valuable to analyse both the short- and mid- to long-term impacts of skin care formulas and better comprehend their effects. The Perfex system also offers a new tool for investigating fundamental questions, such as the link that can exist between dermal proteins and skin surface properties.

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Publication Details

Journal
International Journal of Cosmetic Science
Published
2024-11-12
DOI
https://doi.org/10.1111/ics.13027
Citations
2
Primary Topic
Skin Protection and Aging
Type
article
Field-Weighted Citation Impact
1.07
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article

A new ex vivo human skin model for the topographic and biological analysis of cosmetic formulas

S. Almeida Scalvino, Olivier Jeanneton, Laurent Peno‐Mazzarino, Carine Nizard et al.
2 citations
International Journal of Cosmetic Science
Skin Protection and Aging
1.07
article

A new ex vivo human skin model for the topographic and biological analysis of cosmetic formulas

S. Almeida Scalvino, Olivier Jeanneton, Laurent Peno‐Mazzarino, Carine Nizard, Gallic Beauchef, Karl Pays, Giuseppe Percoco
article en
2 citations

Abstract

The Perfex setup allows for similar preservation of skin explant histology and key protein expression as the conventional system, yet it maintains a skin surface close to that of in vivo skin. Therefore, it is valuable to analyse both the short- and mid- to long-term impacts of skin care formulas and better comprehend their effects. The Perfex system also offers a new tool for investigating fundamental questions, such as the link that can exist between dermal proteins and skin surface properties.

International Journal of Cosmetic ScienceVol. 47(2)
LVMH (France) (FR)
Openalex Percentile: Top 19%
Skin Protection and Aging
1.07
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