A Perspective on the Use of Hydroxyapatites to Improve the Dissolution Behavior of Poorly Water-Soluble Piretanide
Different experimental techniques, in particular spectroscopy and electronic microanalysis, proved the successful loading of piretanide onto doped HAP. Pharmaceutical measurements demonstrated rapid drug release in different fluids simulating gastrointestinal conditions after oral administration. These hybrid systems could be a very promising platform for drug delivery.
Authors
- Marcella Bini (ORCID: https://orcid.org/0000-0001-7099-0650)
- Valeria Friuli (ORCID: https://orcid.org/0000-0002-2975-4362)
- CM Loi
- Lauretta Maggi (ORCID: https://orcid.org/0000-0002-1408-8846)
- Giovanna Bruni (ORCID: https://orcid.org/0000-0003-1958-2998)
Institutions
- University of Pavia (IT)
- National Interuniversity Consortium of Materials Science and Technology (IT)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3390/pharmaceutics16111450
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Dipartimenti di Eccellenza
- Università degli Studi di Pavia
- Ministero dell'Università e della Ricerca