Effects of 5-ion 6-beam sequential irradiation in the presence and absence of hindlimb or control hindlimb unloading on behavioral performances and plasma metabolic pathways of Fischer 344 rats
Phenylalanine, tyrosine, and tryptophan metabolism as well as phenylalanine and tryptophan as plasma metabolites are biomarkers that can be considered for spaceflight as they were revealed in both Fischer and WAG/Rij rats exposed to simGCRsim and/or HU.
Authors
- Breanna Glaeser
- Jeffrey S. Willey (ORCID: https://orcid.org/0000-0001-9927-4586)
- John E. Baker (ORCID: https://orcid.org/0000-0001-7899-3266)
- Christopher M. Olsen (ORCID: https://orcid.org/0000-0003-2700-0310)
- Jan F. Stevens (ORCID: https://orcid.org/0000-0002-6348-9347)
- Jaewoo Choi (ORCID: https://orcid.org/0000-0001-6376-3089)
- Marek Lenarczyk
- Chirayu Patel (ORCID: https://orcid.org/0000-0003-0649-0090)
- Alexander M. Borg (ORCID: https://orcid.org/0000-0002-0476-5735)
- Sarah Holden
- Andy Kwok (ORCID: https://orcid.org/0009-0001-8334-679X)
- Gerd Bobe (ORCID: https://orcid.org/0000-0002-3129-5628)
- Jacob Raber (ORCID: https://orcid.org/0000-0002-9861-9893)
- Jessica Minnier (ORCID: https://orcid.org/0000-0002-3527-2757)
- Kat Kessler
- Alejandro de la Torre (ORCID: https://orcid.org/0000-0002-3902-5294)
- Amy Kronenberg
- Scott Willem Leonard
- Jeffrey T. Morré
- Mitali Chaudhari
Institutions
- Oregon National Primate Research Center (US)
- Oregon State University (US)
- Lawrence Berkeley National Laboratory (US)
- Oregon Health & Science University (US)
- Medical College of Wisconsin (US)
- Wake Forest University (US)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fphys.2024.1486767
- Citations
- 1
- Primary Topic
- Spaceflight effects on biology
- Type
- article
- Field-Weighted Citation Impact
- 0.33