Nutrient transporter pattern in CD56dim NK cells: CD16 (FcγRIIIA)-dependent modulation and association with memory NK cell functional profile
Collectively, our work documents that CD16 engagement leads to a metabolic rewiring of human NK cells and suggests that a distinct nutrient transporter expression pattern may contribute to memory NK cell peculiar functional features.
Authors
- Ricciarda Galandrini (ORCID: https://orcid.org/0000-0003-2660-1456)
- Rosa Molfetta (ORCID: https://orcid.org/0000-0003-2904-6371)
- Davide De Federicis (ORCID: https://orcid.org/0009-0000-1309-6302)
- Cristina Capuano (ORCID: https://orcid.org/0000-0002-6747-3836)
- Daniel Ciuti (ORCID: https://orcid.org/0009-0006-2193-244X)
- Gabriella Palmieri (ORCID: https://orcid.org/0000-0002-1467-1417)
Institutions
- Saint Camillus International University of Health and Medical Sciences (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fimmu.2024.1477776
- Citations
- 4
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- Massachusetts General Hospital
- Ragon Institute of MGH, MIT and Harvard