Genetically predicted smoking and body mass index mediate the relationship between insomnia and myocardial infarction
The results of this MR analysis demonstrate that insomnia increases the risk of MI. Quitting smoking and losing weight may reduce this risk; however, there is still a portion of the impact of insomnia on MI that cannot be explained. Therefore, further investigation into other potentially modifiable intermediate factors is necessary.
Authors
- Yuming Shao (ORCID: https://orcid.org/0000-0001-5254-7882)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-3931-4272)
- Limei Deng (ORCID: https://orcid.org/0000-0002-0670-4231)
- Wan Dongmei
- Wenji Zhai
- Zheng Dong (ORCID: https://orcid.org/0000-0003-0558-268X)
- Qian Xu (ORCID: https://orcid.org/0000-0002-9267-906X)
- Jing Gao (ORCID: https://orcid.org/0000-0002-6525-842X)
Institutions
- Heilongjiang University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fcvm.2024.1456918
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00