Real‐world predictors of dupilumab prescription in patients with chronic rhinosinusitis with nasal polyps
Asthma, AERD, allergic rhinitis, and elevated tissue eosinophil, IL-5, and IL-13 levels are predictive of dupilumab prescription in CRSwNP patients. These may serve as clinical and inflammatory biomarkers and can aid in counseling patients about expected disease trajectory.
Authors
- Mason R. Krysinski (ORCID: https://orcid.org/0000-0002-6156-0349)
- Justin H. Turner (ORCID: https://orcid.org/0000-0002-5501-9900)
- Christina Dorismond (ORCID: https://orcid.org/0000-0002-4333-9763)
- Rory J. Lubner (ORCID: https://orcid.org/0000-0001-9884-2799)
- Naweed I. Chowdhury (ORCID: https://orcid.org/0000-0001-9826-4917)
- Yash Vardhan Trivedi
- Rakesh K. Chandra
Institutions
- University of Alabama at Birmingham (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- International Forum of Allergy & Rhinology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/alr.23483
- Citations
- 9
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 5.22
Funders
- National Institutes of Health
- National Center for Advancing Translational Sciences