Additive effects of cerebrovascular disease functional connectome phenotype and plasma p‐tau181 on longitudinal neurodegeneration and cognitive outcomes
Effects of multiple cerebrovascular disease (CeVD) markers on functional connectivity were studied. A global network phenotype linked to high burden across CeVD markers was identified. CeVD phenotype and plasma phosphorylated tau 181 contributed additively to downstream outcomes.
Authors
- Narayanaswamy Venketasubramanian (ORCID: https://orcid.org/0000-0003-3593-6362)
- Christopher Chen (ORCID: https://orcid.org/0000-0002-1047-9225)
- Fang Ji (ORCID: https://orcid.org/0000-0002-7471-0115)
- Joanna Su Xian Chong (ORCID: https://orcid.org/0009-0008-5077-5206)
- Juan Helen Zhou (ORCID: https://orcid.org/0000-0002-0180-8648)
- Jia Ming Lau
- Joyce Ruifen Chong (ORCID: https://orcid.org/0000-0002-2869-0096)
- Saima Hilal (ORCID: https://orcid.org/0000-0001-5434-5635)
- Mitchell K.P. Lai (ORCID: https://orcid.org/0000-0001-7685-1424)
- Boon Yeow Tan
- Nathanael Ren Jie Tong
Institutions
- National University of Singapore (SG)
- Raffles Institution (SG)
- National University Health System (SG)
- St Luke's Hospital (SG)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/alz.14328
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- Agency for Science, Technology and Research
- National University of Singapore
- Ministry of Education - Singapore
- Ministry of Education, India
- National University Health System
- Medical Research Council
- National Medical Research Council