Evaluation of cross-protection of a reduced-dose PRRS MLV vaccine against the NADC30-like PRRSV challenge
Our research suggests that the MLV vaccine could provide limited protection against the NADC30-like PRRSV infection, and lowering the dosage to 0.01 may produce better protective efficacy. In the context of identifying the immunological target, comprehending the virulence of the virus in the field, and guaranteeing safety, we might be able to reevaluate vaccination dosages to achieve higher economic value.
Authors
- Wensi Wu (ORCID: https://orcid.org/0000-0002-5788-4391)
- Qin Zhao (ORCID: https://orcid.org/0000-0002-3519-9190)
- Xinyu Yan (ORCID: https://orcid.org/0009-0004-5746-5180)
- Nanfang Zeng
- Senyan Du (ORCID: https://orcid.org/0000-0003-3214-9662)
- Sanjie Cao (ORCID: https://orcid.org/0000-0003-2931-0865)
- Yan Li (ORCID: https://orcid.org/0000-0001-7612-3953)
- Yiping Wen (ORCID: https://orcid.org/0000-0002-8098-9933)
- Shan Zhao
- Xiaobo Huang (ORCID: https://orcid.org/0000-0003-3041-5656)
- Shijie Xing (ORCID: https://orcid.org/0000-0001-9733-3407)
- Qigui Yan
- Jiayu Liu (ORCID: https://orcid.org/0000-0002-4172-8802)
Institutions
- Sichuan Agricultural University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fvets.2024.1492173
- Citations
- 2
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.68