Hops bitter β‐acids have antibacterial effects against sinonasal <i>Staphylococcus aureus</i> but also induce sinonasal cilia and mitochondrial dysfunction
Our data suggest that hops β-acids may not be beneficial as treatments in CRS patients and instead contribute to the disease by impairing cell health and further deteriorating the MCC.
Authors
- Ray Z.
- Zoey A. Miller (ORCID: https://orcid.org/0000-0002-1955-4033)
- Yobouet Inès Kouakou
- Robert J. Lee (ORCID: https://orcid.org/0000-0001-5826-6686)
- Noam Cohen (ORCID: https://orcid.org/0009-0003-7047-8843)
- Nithin D. Adappa (ORCID: https://orcid.org/0000-0002-0339-8769)
- Joel C. Thompson
- Li Tan (ORCID: https://orcid.org/0000-0003-4352-654X)
- James Palmer
Institutions
- Monell Chemical Senses Center (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- International Forum of Allergy & Rhinology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/alr.23487
- Citations
- 3
- Primary Topic
- Biochemical Analysis and Sensing Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.93
Funders
- Cystic Fibrosis Foundation
- National Institutes of Health