Antibacterial Activity of Ethanol Extract Red (Jatropha gossypifolia) Leaves Against Bacterial Skin Infections by Agar Diffusion

Red Jatropha gossypifolia plant is a type of Jatropha with purplish red leaves which the chemical compounds are found are calcium oxalate, jatroidene, interquinones, flavonoids, flobatin and phenolics, and these compounds can be used as an anticoagulant, anti-inflammatory, analgesic and antibacterial. The aim of this research is to determine the antibacterial activity of red Jatropha leaves ethanol extract against bacteria causes skin infections by Agar Diffusion. The result of screening antibacterial test of red Jatropha leaves ethanol extract with a concentration of 0,1% active against bacteria Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acne and Pseudomonas aeruginosa. The result of analysis Minimum Inhibitor Concentration (MIC) and Minimum Bactericidal Concentration (MBC) ethanol extract obtained MIC value = 0.1% to bacteria acid, MBC value = 0.05% to bacteria acid, and the result of antibacterial activity of ethanol extract obtained the largest inhibitory zone diameter at a concentration of 12.8% was 13.577 mm against Staphylococcus aureus.