Recompensation of Liver Cirrhosis by <scp>TIPS</scp> Reduces Epithelial Cell Death Markers, Translating Into Improved Clinical Outcome
Correction of portal hypertension via TIPS reduces levels of epithelial cell death markers, indicating that portal hypertension is a driver of outcome-relevant, hepatic cell death in patients with decompensated cirrhosis. Baseline m30/m65 values do not affect six-month survival rates, which suggests that TIPS placement overcomes the unfavourable spontaneous prognosis otherwise indicated by elevated baseline m30/65 levels.
Authors
- Felix Piecha (ORCID: https://orcid.org/0000-0002-2781-5088)
- Gerhard Adam (ORCID: https://orcid.org/0000-0001-7976-3868)
- B.-V. Jahn
- Peter Bannas (ORCID: https://orcid.org/0000-0002-7102-534X)
- Ann‐Kathrin Ozga (ORCID: https://orcid.org/0000-0002-9501-7301)
- Peter Huebener (ORCID: https://orcid.org/0000-0001-7558-7625)
- Johannes Kluwe (ORCID: https://orcid.org/0000-0002-7302-5511)
- Ansgar Wilhelm Lohse (ORCID: https://orcid.org/0000-0002-8823-3129)
- Daniel Benten (ORCID: https://orcid.org/0000-0002-1167-3169)
- Aenne Harberts (ORCID: https://orcid.org/0000-0002-0143-8106)
- Christoph Riedel (ORCID: https://orcid.org/0000-0001-8342-296X)
- Peter Buggisch (ORCID: https://orcid.org/0000-0002-3076-3960)
- Samuel Huber (ORCID: https://orcid.org/0000-0001-9325-8227)
- Amirah Al‐Jawazneh
- Johannes Köntopf
- Anja Koop
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- German Center for Infection Research (DE)
- Institute for Interdisciplinary Medicine (DE)
- Asklepios Klinikum Harburg (DE)
- Bernhard Nocht Institute for Tropical Medicine (DE)
Publication Details
- Journal
- Liver International
- Published
- 2024-11-12
- DOI
- https://doi.org/10.1111/liv.16156
- Citations
- 2
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- Deutsches Zentrum für Infektionsforschung
- Universitätsklinikum Hamburg-Eppendorf