Germ Cell Dysfunction is Universal in Male Patients with β-Thalassemia Following Hematopoietic Stem Cell Transplantation During Childhood and Adolescence
Male patients with β-thalassemia after HSCT experienced universal impaired spermatogenesis and frequent Sertoli cell dysfunction but their Leydig cell function appeared to be preserved. Male patients and/or their guardians should be informed of the high likelihood of future subfertility before HSCT.
Authors
- Wararat Chiangjong (ORCID: https://orcid.org/0000-0002-2984-3330)
- Preamrudee Poomthavorn (ORCID: https://orcid.org/0000-0001-6161-6210)
- Nuttha Piriyapokin
- Pat Mahachoklertwattana (ORCID: https://orcid.org/0000-0002-5670-2963)
- Usanarat Anurathapan (ORCID: https://orcid.org/0000-0002-2791-7471)
Institutions
- Mahidol University (TH)
- Ramathibodi Hospital (TH)
Publication Details
- Journal
- Journal of Clinical Research in Pediatric Endocrinology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.4274/jcrpe.galenos.2024.2024-6-5
- Citations
- 1
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.44