Structural and functional alterations of the hippocampal subfields in <scp>T2DM</scp> with mild cognitive impairment and insulin resistance: A prospective study
The present study found that T2DM-MCI patients have structural and functional alterations in hippocampal subfields, and IR is a negative factor influencing the alteration of hippocampal subfields volume. These findings support the importance of IR in T2DM-MCI patients and might be potential neuroimaging biomarkers of cerebral impairment in T2DM-MCI patients.
Authors
- Yanan Xu (ORCID: https://orcid.org/0000-0002-6747-6981)
- Jing Tian (ORCID: https://orcid.org/0000-0003-0741-8031)
- Lianping Zhao (ORCID: https://orcid.org/0000-0002-1170-771X)
- Jiancang Cao
- Zihan Ma (ORCID: https://orcid.org/0000-0002-7159-4489)
- Wenwen Zhang (ORCID: https://orcid.org/0000-0003-1120-8977)
- Yanjun Fan
- Jian Tan (ORCID: https://orcid.org/0000-0002-2914-0598)
- Gang Huang
- Huiyan Zhang (ORCID: https://orcid.org/0000-0002-8962-2329)
- Chen Yang (ORCID: https://orcid.org/0009-0001-8759-8783)
Institutions
- Gansu Provincial Hospital (CN)
- Ningxia Medical University (CN)
Publication Details
- Journal
- Journal of Diabetes
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1111/1753-0407.70029
- Citations
- 9
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.23
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- Natural Science Foundation of Gansu Province