Cutaneous Metastasis From Gallbladder Carcinoma: A Rare Case

The occurrence of cutaneous metastasis from internal malignancies is relatively rare. Furthermore, cutaneous metastasis from gallbladder carcinoma is an infrequent phenomenon, with only a few reported cases. Here, we report a case of a 45-year-old male with cutaneous metastasis from primary gallbladder carcinoma, initially presenting solely with a scrotal lesion. The lesion was initially misdiagnosed. Later, an abdominal ultrasound performed for another purpose incidentally revealed a mass in the gallbladder, which was subsequently confirmed as gallbladder carcinoma by CT scan (computed tomography scan). Following the diagnosis of gallbladder carcinoma, an incisional biopsy of the lesion was performed due to the suspicion of cutaneous metastasis. Histopathological analyses and the immunohistochemical staining of the biopsy specimen confirmed it as metastatic adenocarcinoma. As for the neoplasm of the gallbladder, skin is a comparatively infrequent site of metastasis, with only a few recorded incidents. Clinicians, especially in regions with a higher incidence of gallbladder carcinoma, should always consider cutaneous metastasis as a differential while treating any abnormal skin lesion in patients with gallbladder carcinoma.

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Journal
Cureus
Published
2024-11-13
DOI
https://doi.org/10.7759/cureus.73633
Primary Topic
Cancer Diagnosis and Treatment
Type
article
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article

Cutaneous Metastasis From Gallbladder Carcinoma: A Rare Case

Dolly Patel, N. Patel, Smita Kothari, Devendra Prasad et al.
Cureus
Cancer Diagnosis and Treatment
article

Cutaneous Metastasis From Gallbladder Carcinoma: A Rare Case

Dolly Patel, N. Patel, Smita Kothari, Devendra Prasad, Alay S Thoria
article en

Abstract

The occurrence of cutaneous metastasis from internal malignancies is relatively rare. Furthermore, cutaneous metastasis from gallbladder carcinoma is an infrequent phenomenon, with only a few reported cases. Here, we report a case of a 45-year-old male with cutaneous metastasis from primary gallbladder carcinoma, initially presenting solely with a scrotal lesion. The lesion was initially misdiagnosed. Later, an abdominal ultrasound performed for another purpose incidentally revealed a mass in the gallbladder, which was subsequently confirmed as gallbladder carcinoma by CT scan (computed tomography scan). Following the diagnosis of gallbladder carcinoma, an incisional biopsy of the lesion was performed due to the suspicion of cutaneous metastasis. Histopathological analyses and the immunohistochemical staining of the biopsy specimen confirmed it as metastatic adenocarcinoma. As for the neoplasm of the gallbladder, skin is a comparatively infrequent site of metastasis, with only a few recorded incidents. Clinicians, especially in regions with a higher incidence of gallbladder carcinoma, should always consider cutaneous metastasis as a differential while treating any abnormal skin lesion in patients with gallbladder carcinoma.

CureusVol. 16(11)
Sardar Vallabhbhai National Institute of Technology Surat (IN), Government Medical College (IN), Government Medical College (IN)
Openalex Percentile: Top 64%
Cancer Diagnosis and Treatment
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Cutaneous Metastasis From Gallbladder Carcinoma: A Rare Case — Dolly Patel, N. Patel, et al. · Cureus (2024) | TGRS Research Map | TGRS