Comprehensive analysis of molecular mechanisms underlying kidney stones: gene expression profiles and potential diagnostic markers
The study comprehensively analyzed gene expression profiles to uncover molecular mechanisms underlying kidney stones. KLK1 and MMP10 were identified as potential diagnostic markers and key players in kidney stone progression. Functional enrichment analysis provided insights into their roles in metabolic processes, immune response, and disease pathology. These results contribute significantly to a better understanding of kidney stone pathogenesis and may inform future diagnostic and therapeutic strategies.
Authors
- Aji Kunnath Devadas
- Gwonhwa Song (ORCID: https://orcid.org/0000-0003-2817-5323)
- Asimujiang Abula
- Aierken Aikebaier
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2024-11-13
- DOI
- https://doi.org/10.3389/fgene.2024.1440774
- Citations
- 3
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- Natural Science Foundation of Xinjiang