Imaging, biomarkers, and vascular cognitive impairment in China: Rationale and design for the VICA study
Establish a large-scale prospective longitudinal cohort comprising 10,000 participants, focusing on the high-risk population of vascular cognitive impairment (VCI) in China. Establish a nationwide three-tier medical network, make full use of resources, and achieve extensive enrollment of patients with cerebral small vessel disease and stroke patients. Utilize multimodal imaging and biomarkers to lay the foundation for constructing more-precise risk models. Introduce eye movement and gait analysis as new methods for assessing cognitive function. Use positron emission tomography to further investigate the interaction between vascular factors and neurodegeneration.
Authors
- Jin‐Tai Yu (ORCID: https://orcid.org/0000-0002-7686-0547)
- Qiang Wei (ORCID: https://orcid.org/0000-0001-5925-6922)
- Junchao Xie (ORCID: https://orcid.org/0000-0002-7620-4689)
- Mei Cui (ORCID: https://orcid.org/0000-0002-6449-8106)
- Junjian Zhang (ORCID: https://orcid.org/0000-0001-7557-4306)
- Qing‐zhang Tuo (ORCID: https://orcid.org/0000-0001-8639-3789)
- Haixia Leng
- Jun Xu (ORCID: https://orcid.org/0000-0001-7432-6781)
- Yanfeng Jiang (ORCID: https://orcid.org/0000-0003-3497-181X)
- Qiang Dong (ORCID: https://orcid.org/0000-0002-3874-0130)
- Jiwei Jiang (ORCID: https://orcid.org/0000-0001-5775-2754)
- Yingzhe Wang (ORCID: https://orcid.org/0000-0002-7382-9683)
- Ding Ding (ORCID: https://orcid.org/0000-0001-8747-6009)
- Kai Wang (ORCID: https://orcid.org/0000-0002-6197-914X)
- Shuting Zhang (ORCID: https://orcid.org/0000-0001-6932-0131)
- Fang Xie (ORCID: https://orcid.org/0000-0002-5327-764X)
- Yanxin Zhao (ORCID: https://orcid.org/0000-0003-4888-264X)
- Lei Peng (ORCID: https://orcid.org/0000-0001-5406-3259)
- Sisi Peng
- Zishuo Jin
- Hongxing Wang (ORCID: https://orcid.org/0009-0000-9803-7503)
Institutions
- Tongji University (CN)
- Capital Medical University (CN)
- Anhui Medical University (CN)
- Sichuan University (CN)
- Fudan University (CN)
- Wuhan University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- West China Hospital of Sichuan University (CN)
- Chinese Institute for Brain Research (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Shanghai Tenth People's Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Huashan Hospital (CN)
- State Key Laboratory of Medical Neurobiology
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/alz.14352
- Citations
- 4
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.99
Funders
- National Key Research and Development Program of China