Daily and Peak Monitor Independent Movement Summary (<scp>MIMS</scp>) Values Associated With Metabolic Syndrome: <scp>NHANES</scp> 2011–12 and 2013–14

The U.S. National Health and Nutrition Examination Survey (NHANES) physical activity monitor datasets for 2011-12 and 2013-14 were released in late 2020. To date, there has been limited interpretation of these nationally representative wrist-worn accelerometer data (summarized and reported in Monitor Independent Movement Summary [MIMS] units) and their relationships with health-related outcomes. This study examined the associations between free-living Daily_MIMS (volume), Peak 1_MIMS and Peak 30_MIMS (intensity), and risk of Metabolic Syndrome (MetS). Data from adults (N=3787; 18-80+ years) in the 2011-12 and 2013-14 NHANES cycles with health examination and accelerometry data were included. Accelerometer data were processed into Peak 1_MIMS and Peak 30_MIMS (MIMS/min), and Daily_MIMS (MIMS/day). Design-based generalized linear and logistic regressions, and a sample-weighted decision tree, were used to examine associations between MIMS variables and MetS risk factors. Lower Peak 1_MIMS, Peak 30_MIMS, and Daily_MIMS were observed for every one-unit increase in the number of risk factors -3.9 [95% CI: -4.3, -3.4] and -2.3 [-2.6, -2.1] MIMS/min, (-672.1 [-772.7, -571.5] MIMS/day, respectively, all p< 0.001). The Decision Tree classified individuals ≥ 46.5 years with a Daily_MIMS ≥ 12 245 MIMS/day and a Peak 30_MIMS < 45.1 MIMS/min as having MetS (≥ 3 risk factors). Individuals < 46.5 years with a Peak 1_MIMS ≥ 62.9 MIMS/min were classified with 0 risk factors. Higher Daily_MIMS and Peak_MIMS were associated with an absence of MetS risk factors, with a progressive decline as the number of risk factors increased. These findings may be considered as preliminary benchmarks for Daily_MIMS and Peak_MIMS associated with cardiometabolic risk.