Cerebral perfusion and amyloidosis in the oldest‐old
Cerebral perfusion and amyloid positron emission tomography (PET) were measured in older adults: 90 years of age and older. Perfusion but not amyloid differed between cognitively impaired and normal groups. Frontal and parietal regions linked to cognitive decline had altered perfusion. Perfusion is related to cognitive status in the oldest-old independent of amyloid.
Authors
- Daniel A. Nation (ORCID: https://orcid.org/0000-0002-9123-0658)
- Shubir Dutt (ORCID: https://orcid.org/0000-0002-8408-2220)
- Dana Greenia
- Davis C. Woodworth (ORCID: https://orcid.org/0000-0002-6256-857X)
- María M. Corrada (ORCID: https://orcid.org/0000-0002-8168-8593)
- S. Ahmad Sajjadi (ORCID: https://orcid.org/0000-0002-8960-2213)
- Charles S DeCarli (ORCID: https://orcid.org/0000-0003-1914-2693)
- Claudia H. Kawas (ORCID: https://orcid.org/0000-0001-9577-230X)
Institutions
- University of Southern California (US)
- University of California, San Francisco (US)
- University of California, Irvine (US)
- University of California, Davis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1002/alz.14357
- Citations
- 1
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- National Institutes of Health
- National Institute on Aging