Comprehensive analysis of single-cell and bulk RNA sequencing reveals postoperative progression markers for non-muscle invasive bladder cancer and predicts responses to immunotherapy

AURKB, GINS2, and UHRF1 have the potential to enhance postoperative management of NMIBC patients undergoing transurethral resection of bladder tumor (TURBT) and can predict immunotherapy response, establishing them as promising therapeutic targets.

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Publication Details

Journal
Discover Oncology
Published
2024-11-13
DOI
https://doi.org/10.1007/s12672-024-01548-2
Citations
7
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
4.01
Controls
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article

Comprehensive analysis of single-cell and bulk RNA sequencing reveals postoperative progression markers for non-muscle invasive bladder cancer and predicts responses to immunotherapy

Zhiliang Xiao, Yuan Wang, Sicong Jiang, Xin Liu et al.
7 citations
Discover Oncology
Bladder and Urothelial Cancer Treatments
4.01
article

Comprehensive analysis of single-cell and bulk RNA sequencing reveals postoperative progression markers for non-muscle invasive bladder cancer and predicts responses to immunotherapy

Zhiliang Xiao, Yuan Wang, Sicong Jiang, Xin Liu, Yan Feng
article en
7 citations

Abstract

AURKB, GINS2, and UHRF1 have the potential to enhance postoperative management of NMIBC patients undergoing transurethral resection of bladder tumor (TURBT) and can predict immunotherapy response, establishing them as promising therapeutic targets.

Discover OncologyVol. 15(1)
Nanchang University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Guangzhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 6%
Bladder and Urothelial Cancer Treatments
4.01
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