Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and their influence on inflammatory biomarkers in pregnancy: Findings from the LIFECODES cohort
The observed suppression of both regulatory (IL-10) and pro-inflammatory (TNF-α) cytokines suggests that PFAS may alter maternal inflammatory processes or immune functions during pregnancy. Further research is needed to understand the effects of both legacy and newer PFAS on inflammatory pathways and their broader clinical implications.
Authors
- John D. Meeker (ORCID: https://orcid.org/0000-0001-8357-5085)
- Kelly K. Ferguson (ORCID: https://orcid.org/0000-0001-8467-3250)
- Thomas F. McElrath (ORCID: https://orcid.org/0000-0003-0857-0107)
- Sean M. Harris (ORCID: https://orcid.org/0000-0001-9852-7270)
- Ram C. Siwakoti (ORCID: https://orcid.org/0000-0001-9284-235X)
- David E. Cantonwine (ORCID: https://orcid.org/0000-0002-3706-9584)
- Bhramar Mukherjee (ORCID: https://orcid.org/0000-0003-0118-4561)
- Wei Hao (ORCID: https://orcid.org/0000-0002-5367-1479)
Institutions
- Brigham and Women's Hospital (US)
- National Institutes of Health (US)
- Harvard University (US)
- University of Michigan (US)
- National Institute of Environmental Health Sciences (US)
Publication Details
- Journal
- Environment International
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.envint.2024.109145
- Citations
- 15
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- National Institutes of Health
- National Institute of Environmental Health Sciences