NCCN Guidelines® Insights: Management of Immunotherapy-Related Toxicities, Version 2.2024
The NCCN Guidelines for the Management of Immunotherapy-Related Toxicities are intended to provide oncology practitioners with guidance on how to manage the wide-ranging and potentially fatal toxicities that may occur with cancer immunotherapy. The guidelines address immune-related adverse events related to immune checkpoint inhibitors, CAR T-cell therapies, and lymphocyte engagers (which include T-cell-engaging bispecific antibodies). These NCCN Guidelines Insights highlight recent guideline updates pertaining to the management of emerging toxicities related to cancer immunotherapy.
Authors
- Bianca Santomasso (ORCID: https://orcid.org/0000-0001-9423-4059)
- Tawnie Braaten (ORCID: https://orcid.org/0000-0002-9121-8958)
- Michael David Jain (ORCID: https://orcid.org/0000-0002-7789-1257)
- Andrew Philip Jallouk (ORCID: https://orcid.org/0000-0003-4335-7942)
- Yaron Gesthalter (ORCID: https://orcid.org/0000-0002-2762-6404)
- Suzanne McGettigan (ORCID: https://orcid.org/0000-0002-7922-8360)
- Zachary Crees (ORCID: https://orcid.org/0000-0003-3215-8454)
- Mohammad Abu Zaid (ORCID: https://orcid.org/0000-0002-4018-6941)
- Julie R. Brahmer (ORCID: https://orcid.org/0000-0002-2443-8395)
- Vlad G. Zaha (ORCID: https://orcid.org/0000-0003-4878-891X)
- Bryan J. Schneider (ORCID: https://orcid.org/0000-0003-4189-3805)
- John A. Thompson (ORCID: https://orcid.org/0000-0002-0872-7306)
- Theresa Michelle Medina (ORCID: https://orcid.org/0000-0003-0579-4121)
- Stephen D. Zucker (ORCID: https://orcid.org/0000-0003-1451-905X)
- Marianne Davies
- Olalekan O. Oluwole (ORCID: https://orcid.org/0000-0001-8525-9641)
- Bonnie L. Bermas (ORCID: https://orcid.org/0000-0002-1007-4084)
- Jordan P. McPherson (ORCID: https://orcid.org/0000-0003-4038-7951)
- Philippe A. Armand (ORCID: https://orcid.org/0000-0001-6098-1603)
- Prantesh Jain (ORCID: https://orcid.org/0000-0003-2771-4612)
- Jason Prosek
- Lisa Hang
- Nisha Mohindra (ORCID: https://orcid.org/0000-0001-5913-1716)
- Sandip Pravin Patel (ORCID: https://orcid.org/0000-0002-8387-4840)
- Mabel M. Ryder (ORCID: https://orcid.org/0000-0002-0520-6505)
- Amaka Achufusi
- Alissa Marr (ORCID: https://orcid.org/0000-0002-2545-3570)
- Maya Khalil
- Meghan Berkenstock (ORCID: https://orcid.org/0000-0001-7517-7706)
- Ajibola Awotiwon (ORCID: https://orcid.org/0000-0003-0887-8670)
- Jeffrey A. Sosman (ORCID: https://orcid.org/0000-0002-0650-9698)
- Anthony J. Olszanski (ORCID: https://orcid.org/0000-0001-5276-5898)
- Tianhong Li (ORCID: https://orcid.org/0000-0001-7422-3520)
- Melissa G. Lechner (ORCID: https://orcid.org/0000-0002-4744-6566)
- Benjamin Harris Kaffenberger (ORCID: https://orcid.org/0000-0001-8079-0011)
- Pankti Reid (ORCID: https://orcid.org/0000-0002-7645-0919)
- Lihua E. Budde (ORCID: https://orcid.org/0000-0003-1464-5494)
- Saurin Chokshi (ORCID: https://orcid.org/0000-0001-7626-8693)
- Huda Salman (ORCID: https://orcid.org/0000-0001-5305-3198)
- Yinghong Wang (ORCID: https://orcid.org/0000-0002-5148-6130)
- Changchun Deng (ORCID: https://orcid.org/0000-0001-9372-6086)
- John Ryan (ORCID: https://orcid.org/0000-0002-2805-8808)
- Sunil Reddy
- Megan Lyons
- Scott Shofer (ORCID: https://orcid.org/0000-0001-9007-6911)
Institutions
- Fox Chase Cancer Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- Barnes-Jewish Hospital (US)
- City Of Hope National Medical Center (US)
- Cleveland Clinic (US)
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa (ZA)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Tennessee Health Science Center (US)
- Breast Cancer Research Foundation (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- UC San Diego Health System (US)
- Huntsman Cancer Institute (US)
- Cancer Institute (WIA) (IN)
- Susan Thompson Buffett Foundation (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Moffitt Cancer Center (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Jewish Hospital (US)
- University of Wisconsin Carbone Cancer Center (US)
- Sidney Kimmel Cancer Center (US)
- Dana-Farber Cancer Institute (US)
- University Hospitals Seidman Cancer Center (US)
- Duke Medical Center (US)
- University of Colorado Cancer Center (US)
- Patient Advocate Foundation (US)
- Dana-Farber Brigham Cancer Center (US)
- Smilow Cancer Hospital (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Moores Cancer Center
- University of Chicago Medicine Comprehensive Cancer Center
- UCLA Jonsson Comprehensive Cancer Center
- Vanderbilt-Ingram Cancer Center
- Stanford Cancer Institute
- Duke Cancer Institute
- Fred and Pamela Buffett Cancer Center
- UC Davis Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- O'Neal Comprehensive Cancer Center
- National Comprehensive Cancer Network
- Indiana University (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of the National Comprehensive Cancer Network
- Published
- 2024-11-01
- DOI
- https://doi.org/10.6004/jnccn.2024.0057
- Citations
- 83
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 23.17