Customized immunotherapy in OSCC: Leveraging neoantigens for precision medicine
• Neoantigens enhance targeted immunotherapy in oral squamous cell carcinoma. • Personalized cancer vaccines activate T cells against tumor-specific antigens. • Adoptive T cell therapy utilizes patient's T cells for targeted cancer attack. • Combining neoantigens with checkpoint inhibitors boosts immune response. • Overcoming challenges will improve the feasibility of neoantigen therapies.
Authors
- Nitya Krishnasamy
- Vikram S. Amberkar
- Kochli Channapa Niranjan
Institutions
- Sri Dharmasthala Manjunatheshwara College of Dental Sciences & Hospital (IN)
- Bapuji Dental College and Hospital (IN)
- Saveetha University (IN)
Publication Details
- Journal
- Oral Oncology Reports
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.oor.2024.100687
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00