Elucidating common biomarkers and pathways of osteoporosis and aortic valve calcification: insights into new therapeutic targets
The study clarifies shared mechanisms of osteoporosis and aortic valve calcification, identifies biomarkers, and highlights TNFSF11, KYNU, and HLA-DMB. It also suggests 17-beta-estradiol and vitamin D3 as potential effective treatments.
Authors
- Qinglin Peng (ORCID: https://orcid.org/0000-0002-1271-1729)
- Yujian Lan
- Huan Liu (ORCID: https://orcid.org/0000-0003-2937-0198)
- Jianlin Shen
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Putian University (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1038/s41598-024-78707-6
- Citations
- 2
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China