Euphorbiasteroid induces neurotoxicity through the FOXO/NF-κB/apoptosis signaling pathway
Euphorbiasteroid induces neurotoxicity through the activation of the FOXO/NF-κB/apoptosis signaling pathway. These findings provide new insights into the mechanisms of euphorbiasteroid-induced neurotoxicity and suggest potential strategies to mitigate these effects, which is crucial for its therapeutic application.
Authors
- Zhengxu Cai (ORCID: https://orcid.org/0000-0003-0239-9601)
- Jianwen Chen (ORCID: https://orcid.org/0000-0002-4438-7898)
- Yuheng Wang (ORCID: https://orcid.org/0000-0001-5252-7005)
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.brainresbull.2024.111129
- Citations
- 2
- Primary Topic
- FOXO transcription factor regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.47