Synthesis of prodelphinidin B2 3,3′′-digallate using AgOTf-mediated self-condensation
The Lewis acid mediated self-condensation of an epigallocatechin gallate derivative was examined. We found that AgOTf as a Lewis acid and diethylene glycol as a leaving group at C-4 position afforded a dimeric epigallocatechin gallate derivative in a moderate yield. The condensed product was applied to the synthesis of prodelphinidin B2 3,3′′-digallate.
Authors
- Hiromu Saito (ORCID: https://orcid.org/0000-0002-0627-7890)
- Atsushi Kawamura (ORCID: https://orcid.org/0000-0003-4464-883X)
- Yoriko Takahashi
- Hidefumi Makabe (ORCID: https://orcid.org/0000-0001-9136-6865)
Institutions
- Shinshu University (JP)
Publication Details
- Journal
- Results in Chemistry
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.rechem.2024.101902
- Primary Topic
- Phytochemical compounds biological activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shinshu University
- Japan Society for the Promotion of Science