Upregulation of multiple key molecules is correlated with poor prognosis and immune infiltrates in hepatocellular carcinoma by bulk and single-cell RNA-seq
The results from differential analysis using three R packages are robust, revealing genes closely linked to immune cell infiltration in the tumor microenvironment. Additionally, a validated prognostic model for liver cancer was established based on key genes.
Authors
- Xutong Li (ORCID: https://orcid.org/0000-0002-6864-9872)
- He Yan (ORCID: https://orcid.org/0000-0003-2854-4387)
- Jiaying Liu (ORCID: https://orcid.org/0000-0002-5537-7628)
- Hao Gu (ORCID: https://orcid.org/0000-0002-8742-4839)
- Linyan Zhao
Institutions
- Hebei Medical University (CN)
- Anhui Medical University (CN)
- Xingtai People's Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Aging
- Published
- 2024-11-12
- DOI
- https://doi.org/10.18632/aging.206151
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00