Longitudinal Follow-up Reveals Peripheral Immunological Changes Upon Tick Bite in α-Gal–Sensitized Individuals
Our study provides evidence of significant changes in several immune cell populations in α-Gal-sensitized patients, along with increased levels of IL-8 and sIgE. This is the first exploratory study to investigate longitudinal peripheral immune profiles in patients and controls bitten by ticks.
Authors
- Ute Mackenstedt
- F Hedin
- T Biedermann
- Christiane Hilger (ORCID: https://orcid.org/0000-0001-9455-5442)
- Antonio Cosma (ORCID: https://orcid.org/0000-0002-3686-8034)
- Markus W. Ollert (ORCID: https://orcid.org/0000-0002-8055-0103)
- Kyra Swiontek
- Jörg Fischer (ORCID: https://orcid.org/0000-0001-6305-6659)
- Neera Chakrapani (ORCID: https://orcid.org/0000-0002-6015-2933)
- Simon Riel (ORCID: https://orcid.org/0000-0002-6618-9905)
- Dominique Revets
- Annette Kuehn (ORCID: https://orcid.org/0000-0003-0474-2135)
Institutions
- University of Hohenheim (DE)
- University of Southern Denmark (DK)
- Luxembourg Institute of Health (LU)
- Technical University of Munich (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Journal of Investigational Allergology and Clinical Immunology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.18176/jiaci.1028
- Citations
- 3
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.15