Exosomal PSM-E inhibits macrophage M2 polarization to suppress prostate cancer metastasis through the RACK1 signaling axis
Notably, exosomes carrying PSM-E from PCa urine could potentially serve as a biomarker for PCa, and targeting exosomal PSM-E may represent a strategy for preventing tumor progression in this patient population.
Authors
- Yongyao Tan (ORCID: https://orcid.org/0000-0003-0715-0215)
- Xingliang Qin (ORCID: https://orcid.org/0000-0003-4440-0287)
- Hongyu Guan (ORCID: https://orcid.org/0000-0002-1818-5467)
- Weiwei Zhou (ORCID: https://orcid.org/0000-0003-1641-8965)
- Mingze Xu (ORCID: https://orcid.org/0000-0002-3440-4500)
- Yu Chen (ORCID: https://orcid.org/0000-0002-5254-200X)
- Jun‐Long Zhang (ORCID: https://orcid.org/0000-0002-5731-7354)
- Xun Zhu (ORCID: https://orcid.org/0000-0001-5376-490X)
- Yuxin Huang (ORCID: https://orcid.org/0000-0003-3056-4168)
- Huiquan Wu
- Xiang Zhou (ORCID: https://orcid.org/0000-0002-4904-4245)
- Rouxi Niu
- Kaiyuan Cao
- Weishu Ren
Institutions
- Sun Yat-sen University (CN)
- Chinese University of Hong Kong (HK)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Guangzhou Electronic Technology (China) (CN)
Publication Details
- Journal
- Biomarker Research
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s40364-024-00685-8
- Citations
- 7
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Natural Science Foundation of China
- Basic and Applied Basic Research Foundation of Guangdong Province