Periplaneta americana L. extract exerts neuroprotective effects by inhibiting endoplasmic reticulum stress via AKT-dependent pathway in experimental models of Parkinson’s disease
Our results suggest that P. americana exerts neuroprotective effects through inhibiting ER stress via AKT-dependent pathway. Periplaneta americana may represent a promising therapeutic agent for PD treatment and is worthy of further being exploited.
Authors
- Zhen Tian (ORCID: https://orcid.org/0000-0001-9044-637X)
- Jiangyan Rao
- Hongyi Qi (ORCID: https://orcid.org/0000-0003-0564-3892)
- Zhu Hui-feng
- Xuelian Wang (ORCID: https://orcid.org/0000-0002-4647-3693)
- Ting Cao (ORCID: https://orcid.org/0000-0001-7530-4859)
Institutions
- Southwest University (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s13020-024-01029-2
- Citations
- 7
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.29
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Chongqing