Euphorbium compositum SN improves the innate defenses of the airway mucosal barrier network during rhinovirus infection
ECSN6 prevents RV-induced airway mucosal barrier dysfunction and improves the immunological and mucociliary barrier function. ECSN6 may maintain integrity of barrier function by promoting localization of tight and adherence junction proteins to the IJ. This in turn may lead to the observed decrease in RV-induced pro-inflammatory responses in vitro. By improving the innate defenses of the airway mucosal barrier network, ECSN6 may alleviate respiratory symptoms caused by RV infections.
Authors
- Haleh Ganjian (ORCID: https://orcid.org/0000-0001-7420-9307)
- Julia Dannenmaier
- Kathrin Weyer (ORCID: https://orcid.org/0000-0002-8473-7987)
- Bernd Seilheimer (ORCID: https://orcid.org/0000-0002-9108-5892)
- Umadevi S. Sajjan
- Ganesh Muruganandam
- Charu Rajput
Institutions
- Heel (Germany) (DE)
- Temple University Health System (US)
- Temple University (US)
Publication Details
- Journal
- Respiratory Research
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s12931-024-03030-7
- Citations
- 1
- Primary Topic
- Pediatric health and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- Temple University