Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases
ORs in the lung epithelium might be involved in airway-sensitivity to odorants. Their antagonism could represent a promising strategy in treatment of odorant-induced asthma with non-type 2 inflammation.
Authors
- Jürgen Knobloch (ORCID: https://orcid.org/0000-0001-6868-0055)
- Christian Taube (ORCID: https://orcid.org/0000-0002-3546-1398)
- Sebastian Reuter (ORCID: https://orcid.org/0000-0002-1784-0124)
- Natalie Heinen (ORCID: https://orcid.org/0000-0003-0906-5073)
- Hanns Hatt
- Marcus Peters (ORCID: https://orcid.org/0000-0003-1850-2845)
- Noha Awad (ORCID: https://orcid.org/0000-0001-6805-6033)
- Lea Greune
- Juliane Kronsbein
- Stephanie Pfaender (ORCID: https://orcid.org/0000-0002-3957-5448)
- Anke C. Fender (ORCID: https://orcid.org/0000-0003-3965-6165)
- Daniel Weidinger (ORCID: https://orcid.org/0000-0003-1468-0273)
- Saskia Westhoven (ORCID: https://orcid.org/0009-0002-0618-3752)
Institutions
- Ain Shams University (EG)
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- BG University Hospital Bergmannsheil Bochum (DE)
- University of Duisburg-Essen (DE)
- Ruhr University Bochum (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Cell Biology and Toxicology
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1007/s10565-024-09935-9
- Citations
- 4
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.44
Funders
- Deutsche Forschungsgemeinschaft
- Ruhr-Universität Bochum