MicroRNAome profiling of breast cancer unveils hsa-miR-5683 as a tumor suppressor microRNA predicting favorable clinical outcome
Our data provides comprehensive miRNA expression atlas in breast cancer subtypes and underscores the prognostic and therapeutic significance of numerous miRNAs, including hsa-miR-5683 in TNBC. The identified gene targets unravel the intricate regulatory network in TNBC progression, suggesting promising avenues for further research and targeted therapeutic interventions.
Authors
- Ramesh Elango (ORCID: https://orcid.org/0000-0003-1762-1834)
- Radhakrishnan Vishnubalaji
- Nehad M. Alajez (ORCID: https://orcid.org/0000-0002-1546-1091)
- Hibah Shaath (ORCID: https://orcid.org/0000-0003-3576-7626)
- Mohammed Akhtar (ORCID: https://orcid.org/0000-0002-0722-7967)
- Sameera Rashid (ORCID: https://orcid.org/0000-0003-0608-4746)
- Reem Al-Sarraf
- Bushra Yasin Abohalawa
Institutions
- The Christie NHS Foundation Trust (GB)
- Hamad bin Khalifa University (QA)
- Hamad Medical Corporation (QA)
- Qatar Foundation (QA)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s12935-024-03550-8
- Citations
- 3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- Fonds National de la Recherche Luxembourg
- Qatar National Research Fund
- Qatar Biomedical Research Institute, Hamad Bin Khalifa University