Assessing the causal associations of atrial fibrillation with serum uric acid level and gout: insights from a bidirectional mendelian randomization study
Our findings challenge the widely held belief that lowering urate levels is uniformly effective in reducing the risk of atrial fibrillation (AF). Our study fails to substantiate the existence of a causal link between uric acid (UA) levels or gout and the development of AF, regardless of direction.
Authors
- Fengfeng Deng (ORCID: https://orcid.org/0000-0002-0998-8516)
- Mingfang Zhang (ORCID: https://orcid.org/0000-0002-9248-0712)
- Chengjie Wang (ORCID: https://orcid.org/0009-0009-2803-5137)
- Shuai Zhu (ORCID: https://orcid.org/0000-0003-2187-114X)
- Shanshan Cheng (ORCID: https://orcid.org/0000-0002-6953-0136)
Institutions
- Huangshan University (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s12872-024-04319-7
- Citations
- 2
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 0.68