Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor

Situs viscerum inversus totalis (SIT) is a rare congenital anomaly. Deceased donors with this condition are often declined because of the technical issues in both the organ's procurement and its transplant. Only eight cases of deceased donor organs with SIT were reported to be used for liver transplantation (LT). We herein present a case of LT using a graft from an SIT donor: a modified retroversus piggyback technique was used. A 15 year-old female was referred to our institution as a potential donor. An SIT condition was discovered during standard donor evaluation together with the presence of a complex triple arterial pedicle. Procurement operative time was 125 min, from skin incision to cross-clamp. Liver extraction occurred 32 min after cold flush. The recipient was a 56 year-old male affected by recurrent hepatocellular carcinoma (HCC) on hepatitis C related liver cirrhosis. Position and orientation trials of the graft were made and it was decided to implant it with the retroversus technique. Direct duct-to-duct biliary reconstruction was achieved. The postoperative course was uneventful. To our knowledge, this is the first implant with retroversus technique combined to direct biliary reconstruction and the first repetition of that technique. Cases like this highlight how technical complexity can be overcome leading to successful management of difficult scenarios in a safe manner.

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Publication Details

Journal
Updates in Surgery
Published
2024-11-13
DOI
https://doi.org/10.1007/s13304-024-01968-3
Primary Topic
Metabolism and Genetic Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor

Stefano Di Sandro, Fabrizio Di Benedetto, Gian Piero Guerrini, Paolo Magistri et al.
Updates in Surgery
Metabolism and Genetic Disorders
article

Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor

Stefano Di Sandro, Fabrizio Di Benedetto, Gian Piero Guerrini, Paolo Magistri, Barbara Catellani, Philip C. Müller, Roberta Odorizzi, Cristiano Guidetti
article en

Abstract

Situs viscerum inversus totalis (SIT) is a rare congenital anomaly. Deceased donors with this condition are often declined because of the technical issues in both the organ's procurement and its transplant. Only eight cases of deceased donor organs with SIT were reported to be used for liver transplantation (LT). We herein present a case of LT using a graft from an SIT donor: a modified retroversus piggyback technique was used. A 15 year-old female was referred to our institution as a potential donor. An SIT condition was discovered during standard donor evaluation together with the presence of a complex triple arterial pedicle. Procurement operative time was 125 min, from skin incision to cross-clamp. Liver extraction occurred 32 min after cold flush. The recipient was a 56 year-old male affected by recurrent hepatocellular carcinoma (HCC) on hepatitis C related liver cirrhosis. Position and orientation trials of the graft were made and it was decided to implant it with the retroversus technique. Direct duct-to-duct biliary reconstruction was achieved. The postoperative course was uneventful. To our knowledge, this is the first implant with retroversus technique combined to direct biliary reconstruction and the first repetition of that technique. Cases like this highlight how technical complexity can be overcome leading to successful management of difficult scenarios in a safe manner.

Updates in SurgeryVol. 77(1)
University of Modena and Reggio Emilia (IT), Azienda Ospedaliero-Universitaria di Modena (IT), Institute of Molecular and Clinical Ophthalmology Basel (CH)
Università Degli Studi di Modena e Reggio Emila
Good health and well-being
Openalex Percentile: Top 70%
Metabolism and Genetic Disorders
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