Dosing, Toxicity and Drug Concentrations for Ganciclovir/Valganciclovir in Preterm and Low Birthweight Infants Treated for Cytomegalovirus
GCV and valGCV use among preterm and very low birthweight infants with CMV disease resulted in a higher incidence of adverse events, increased AUC0-12h and elevated Cmin compared with term infants. Further pharmacokinetic studies are necessary to determine the ideal dosage in this population.
Authors
- Asrar Abu Bakar (ORCID: https://orcid.org/0009-0008-6138-1077)
- Tom Jacobs (ORCID: https://orcid.org/0000-0001-5738-5528)
- Helen Payne (ORCID: https://orcid.org/0000-0003-2028-1121)
- Muhd Alwi Muhd Helmi (ORCID: https://orcid.org/0000-0001-5259-6289)
- Neil Tickner
- Hermione Lyall (ORCID: https://orcid.org/0000-0001-6114-7215)
Institutions
- Radboud University Nijmegen (NL)
- Imperial College Healthcare NHS Trust (GB)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- International Islamic University Malaysia (MY)
- Tergooi (NL)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1097/inf.0000000000004605
- Citations
- 7
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 2.71