Utility of Multiparametric Prostate MRI to Predict Regional or Distant Metastatic Disease Against Conventional Staging Using CT and Bone Scintigraphy or 68Ga-PSMA PET in Intermediate-to-High-Risk Prostate Cancer

The impression of nodal and metastatic status through mpMRI poorly correlates with results from conventional staging and PSMA-PET. PSMA-PET more often produces discordant results to mpMRI, signifying an additive diagnostic value. MRI should not be used alone in the workup of prostate cancer in patients with a GS ≥ 7, where metastasis is a concern.

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Publication Details

Journal
Cureus
Published
2024-11-13
DOI
https://doi.org/10.7759/cureus.73607
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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article

Utility of Multiparametric Prostate MRI to Predict Regional or Distant Metastatic Disease Against Conventional Staging Using CT and Bone Scintigraphy or 68Ga-PSMA PET in Intermediate-to-High-Risk Prostate Cancer

Minhtuan Nguyenhuy, David Homewood, Xiang Qian Chan, Philip Dundee et al.
Cureus
Prostate Cancer Diagnosis and Treatment
article

Utility of Multiparametric Prostate MRI to Predict Regional or Distant Metastatic Disease Against Conventional Staging Using CT and Bone Scintigraphy or 68Ga-PSMA PET in Intermediate-to-High-Risk Prostate Cancer

Minhtuan Nguyenhuy, David Homewood, Xiang Qian Chan, Philip Dundee, Cindy Ogluszko, Niall M. Corcoran
article en

Abstract

The impression of nodal and metastatic status through mpMRI poorly correlates with results from conventional staging and PSMA-PET. PSMA-PET more often produces discordant results to mpMRI, signifying an additive diagnostic value. MRI should not be used alone in the workup of prostate cancer in patients with a GS ≥ 7, where metastasis is a concern.

CureusVol. 16(11)
The Royal Melbourne Hospital (AU), Western Health (AU), Austin Health (AU)
Good health and well-being
Openalex Percentile: Top 62%
Prostate Cancer Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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Utility of Multiparametric Prostate MRI to Predict Regional or Distant Metastatic Disease Against Conventional Staging Using CT and Bone Scintigraphy or 68Ga-PSMA PET in Intermediate-to-High-Risk Prostate Cancer — Minhtuan Nguyenhuy, David Homewood, et al. · Cureus (2024) | TGRS Research Map | TGRS