Radiomics and molecular analysis: Bridging the gap for predicting hepatocellular carcinoma prognosis

This editorial examines a recent study that used radiomics based on computed tomography (CT) to predict the expression of the fibroblast-related gene enhancer of zeste homolog 2 (<i>EZH2</i>) and its correlation with the survival of patients with hepatocellular carcinoma (HCC). By integrating radiomics with molecular analysis, the study presented a strategy for accurately predicting the expression of <i>EZH2</i> from CT scans. The findings demonstrated a strong link between the radiomics model, <i>EZH2</i> expression, and patient prognosis. This noninvasive approach provides valuable insights into the therapeutic management of HCC.