Exploring and Validating the Mechanism of Ulinastatin in the Treatment of Sepsis-Associated Encephalopathy Based on Transcriptome Sequencing
In conclusion, <i>ICAM-1, IRF7, IL-1β, CCL2, IL-6</i>, and <i>SOCS3</i> were identified as potential therapeutic targets in SAE mice treated with UTI. This study offers theoretical support for UTI as a treatment option for SAE.
Authors
- Bailong Hu (ORCID: https://orcid.org/0000-0003-1126-5381)
- Yang Luo (ORCID: https://orcid.org/0000-0001-7385-6166)
- Wen Hu (ORCID: https://orcid.org/0000-0002-4329-6900)
- Xiaohua Zou (ORCID: https://orcid.org/0000-0002-3489-9152)
- Xiaoyuan Zhang (ORCID: https://orcid.org/0000-0002-0179-9032)
- Zhenhua Wu (ORCID: https://orcid.org/0000-0003-4552-883X)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2024-11-01
- DOI
- https://doi.org/10.2147/jir.s488400
- Citations
- 3
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.70