TH17/Treg lymphocyte balance is regulated by beta adrenergic and cAMP signaling
Our data depict a novel role for β1/2 adrenergic and cAMP signaling in the balance of T<sub>H</sub>17/Treg lymphocytes. These findings provide a new target for pharmacological therapy in both psychiatric and autoimmune diseases associated with IL-17A-related pathology.
Authors
- Tatlock Lauten (ORCID: https://orcid.org/0000-0002-9325-7213)
- Adam J. Case
- Emily C. Reed (ORCID: https://orcid.org/0000-0001-6487-5111)
- Safwan Elkhatib (ORCID: https://orcid.org/0000-0003-3946-8658)
- Tamara Natour (ORCID: https://orcid.org/0009-0005-1084-464X)
- Caroline N Jojo
Institutions
- Brigham and Women's Hospital (US)
- Texas A&M Health Science Center (US)
- Bryan College (US)
Publication Details
- Journal
- Brain Behavior and Immunity
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1016/j.bbi.2024.11.013
- Citations
- 15
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 3.71
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Institute of General Medical Sciences