Lipoprotein-associated phospholipase A2 and its possible association with COPD development: a case-control study
Our preliminary study suggests that Lp-PLA2 is independently associated with diffuse pulmonary emphysema, obstructive ventilatory dysfunction as well as small airway dysfunction, which are commonly seen in COPD development. These findings indicated a possible association between Lp-PLA2 and COPD, though further validation is needed in a large cohort of COPD patients.
Authors
- Jie Zhou (ORCID: https://orcid.org/0000-0003-0767-0835)
- Yu He (ORCID: https://orcid.org/0009-0009-4487-1047)
- Mingxia Wu (ORCID: https://orcid.org/0009-0004-6433-2650)
- Zongtao Chen (ORCID: https://orcid.org/0000-0001-7022-8666)
- Ying Yang
Institutions
- Army Medical University (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2024-11-13
- DOI
- https://doi.org/10.1186/s12890-024-03335-9
- Citations
- 2
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84