KDM4A facilitates neuropathic pain and microglial M1 polarization by regulating BDNF in a rat model of brachial plexus avulsion
Current findings suggest that the upregulation of KDM4A increases BDNF expression in the spinal cord in rats after BPA, contributing to microgliosis, neuroinflammation, and neuropathic pain.
Authors
- Jinding Guo
- Chengpeng Liao (ORCID: https://orcid.org/0009-0002-6122-9696)
- Jie Lao (ORCID: https://orcid.org/0000-0003-4343-6050)
- Xi Chen (ORCID: https://orcid.org/0009-0007-9593-316X)
- Jing Rui (ORCID: https://orcid.org/0000-0003-3587-5985)
- Kaiming Gao
- Yingjie Zhou (ORCID: https://orcid.org/0009-0008-7193-3197)
Institutions
- Fudan University (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Regional Anesthesia & Pain Medicine
- Published
- 2024-11-12
- DOI
- https://doi.org/10.1136/rapm-2024-105801
- Citations
- 3
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- National Natural Science Foundation of China