The dynamic range of immunoassays for heparin-induced thrombocytopenia

Despite both immunoassays showing an association between results and diagnostic significance, the strength of the association varies by assay. CLIA has a larger increase per measurement unit. Posttest probabilities for individual patients can be estimated using a web-based calculator: https://pcd-research.shinyapps.io/BayesianCalculator/.

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Publication Details

Journal
Journal of Thrombosis and Haemostasis
Published
2024-11-12
DOI
https://doi.org/10.1016/j.jtha.2024.10.026
Primary Topic
Heparin-Induced Thrombocytopenia and Thrombosis
Type
article
Field-Weighted Citation Impact
0.00

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article

The dynamic range of immunoassays for heparin-induced thrombocytopenia

Michael Nagler, Christos Theodoros Nakas, S. Naas, Prakash Vishnu et al.
Journal of Thrombosis and Haemostasis
Heparin-Induced Thrombocytopenia and Thrombosis
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The dynamic range of immunoassays for heparin-induced thrombocytopenia

Michael Nagler, Christos Theodoros Nakas, S. Naas, Prakash Vishnu, Lukas Graf, Bernhard Gerber, Walter A. Wuillemin, Tamam Bakchoul, Johanna A. Kremer Hovinga, Henning Nilius, Adrian Schmidt, Dimitrios Α. Tsakiris, Andreas Greinacher, Adriana Méndez, Jan–Dirk Studt
article en

Abstract

Despite both immunoassays showing an association between results and diagnostic significance, the strength of the association varies by assay. CLIA has a larger increase per measurement unit. Posttest probabilities for individual patients can be estimated using a web-based calculator: https://pcd-research.shinyapps.io/BayesianCalculator/.

Journal of Thrombosis and HaemostasisVol. 23(2)
University of Lucerne (CH), University of St.Gallen (CH), Universitätsmedizin Greifswald (DE), Triemli Hospital (CH), University Hospital of Bern (CH), University Hospital of Basel (CH), Fred Hutch Cancer Center (US), University Hospital of Zurich (CH), Institute of Oncology Research (CH), Kantonsspital Aarau (CH)
International Society on Thrombosis and Haemostasis, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Openalex Percentile: Top 62%
Heparin-Induced Thrombocytopenia and Thrombosis
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